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Why Is Only One Knee Swollen?

Posted on July 7, 2025

If you’re experiencing swelling in just one knee, there could be several possible causes. Here are some of the most common reasons and when to seek medical attention:

Table of Contents

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  • Possible Causes of One Swollen Knee:
  • When to See a Doctor:
  • At-Home Care (Mild Cases):

Possible Causes of One Swollen Knee:

  1. Trauma or Injury

    • Sprains, strains, or ligament tears (e.g., ACL injury)

    • Fractures or meniscus tears

    • Bursitis (inflammation of the fluid-filled sacs around the knee)

  2. Infections (Septic Arthritis)

    • Bacterial or viral infections can cause sudden, painful swelling, often with fever.

    • Requires immediate medical treatment to prevent joint damage.

  3. Gout or Pseudogout

    • Gout (uric acid crystals) causes sudden, severe pain, redness, and swelling.

    • Pseudogout (calcium crystals) has similar symptoms but is less common.

  4. Osteoarthritis (Wear-and-Tear Arthritis)

    • Typically affects one knee more than the other, especially in older adults.

    • May cause stiffness, pain, and swelling after activity.

  5. Rheumatoid Arthritis (Autoimmune Condition)

    • Usually affects both knees, but early stages may start on one side.

  6. Baker’s Cyst (Popliteal Cyst)

    • A fluid-filled sac behind the knee that can cause swelling and stiffness.

  7. Blood Clot (Deep Vein Thrombosis – DVT)

    • If swelling is accompanied by warmth, redness, and calf pain, seek emergency care (risk of pulmonary embolism).

When to See a Doctor:

✔ Severe pain or inability to bear weight
✔ Fever, redness, or warmth (signs of infection)
✔ Sudden swelling after an injury
✔ Swelling lasting more than 3 days without improvement

At-Home Care (Mild Cases):

  • R.I.C.E. Method: Rest, Ice, Compression, Elevation

  • Over-the-counter pain relievers (NSAIDs like ibuprofen, if no contraindications)

If swelling persists or worsens, consult a healthcare provider for proper diagnosis (possibly X-rays, ultrasound, or fluid aspiration).

Would you like help identifying specific symptoms you’re experiencing?

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